Trifloxysulfuron

Trifloxysulfuron

三氟啶磺隆

1-(4,6-dimethoxypyrimidin-2-yl)-3-[3-(2,2,2-trifluoroethoxy)-2-pyridylsulfonyl]urea

N-[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]-3-(2,2,2-trifluoroethoxy)-2-pyridinesulfonamide

145099-21-4,199119-58-9

C₁₄H₁₄F₃N₅O₆S

Herbicides > Sulfonylurea Herbicides

Herbicide

Molecular weight:459.3 (sodium salt); 437.4 (acid); Physical form:Odourless, white to off-white powder. Density:1.63 g/cm3 (21 °C); Melting point:170.2-177.7 °C; Vapour pressure:<0.01 mPa (25 °C); Henry constant:2.6 ×10-5 Pa m3 mol-1 ( calc.); Partition coefficient(n-octanol and water):logP = -0.43 ( pH 7, 25 °C); pKa:4.76 (20 °C); Solubility:In water 5016 mg/l ( pH 7, 25 °C).; Stability:Hydrolysis DT50 20 d (pH 7, 25 °C); photolysis DT50 7 h (25 °C).;

Oral:Acute oral LD₅₀ for rats >5000 mg/kg. Percutaneous:Acute percutaneous LD₅₀ for rats >2000 mg/kg. Non-irritating to skin and eyes (rabbits). Not a skin sensitiser (guinea pigs). Inhalation: LC₅₀ for rats (4 h) >5.03 mg/l.

Ecotoxicology: 
Algae: IC₅₀ (120 h) for Navicula >150, Skeletonema 80, Anabaena 0.28, Selenastrum 0.0065 mg/l.Bees:LD₅₀ (48 h) (oral and contact) >25 µg/bee.Birds: LD₅₀ for mallard ducks >2000, bobwhite quail >2250 mg/kg. Dietary NOEC for mallard ducks and bobwhite quail 5620 ppm.Daphnia: EC₅₀ (48 h) >108 mg/l.Fish: LC₅₀ (96 h) for rainbow trout and bluegill sunfish >103 mg/l.Worms:Acute LC₅₀ (14 d) >1000 mg/kg soil.Other aquatic spp.: EC₅₀ (96 h) for Eastern oyster >103 mg/l.Other beneficial spp.:Not harmful to Typhlodromus, Aphidius, Poecilus; no effect on soil microbes (respiration, nitrification) or on activated sewage sludge. 

Environmental fate: 
Trifloxysulfuron is rapidly absorbed and degraded, and shows no tendency to accumulate in organisms or the environment.Animals:Rapidly absorbed and excreted (c. 70% via urine, 6% via faeces); after 7 d, remaining residues were <0.3% of dose; metabolism is via O-demethylation, bridge cleavage, glucuronide conjugation.Soil:Soil adsorption K_oc 29-584 ml/cm³ depending on soil type and pH; increasing adsorption over time; DT₅₀ (20 °C, 40% MWC; various soils) 49-78 d. Aqueous

Hazard Class:III(Slightly hazardous)