Tetramethrin

Tetramethrin

胺菊酯

cyclohex-1-ene-1,2-dicarboximidomethyl (1RS,3RS;1RS,3SR)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate
or
cyclohex-1-ene-1,2-dicarboximidomethyl (1RS)-cis-trans-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate
or
cyclohex-1-ene-1,2-dicarboximidomethyl (±)-cis-trans-chrysanthemate

(1,3,4,5,6,7-hexahydro-1,3-dioxo-2H-isoindol-2-yl)methyl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate

7696-12-0

C₁₉H₂₅NO₄

Insecticides > Pyrethroid insecticides
Insecticides > Phthalimide insecticides

Tetramethrin, the second generation of synthetic pyrethroids, is a contact insecticide with a rapid knockdown action on flies, mosquitoes, cockroaches, wasps and other insect pests in public, home and garden primarily for indoor pest control uses.

 flies, mosquitoes, cockroaches, wasps and other insect pests.

AE = Aerosol dispenser
DP = Dustable powder
OL = Oil miscible liquide

Permethrin+tetramethrin
Permethrin+Piperonyl butoxide+tetramethrin
Lambda-cyhalothrin+Piperonyl butoxide+tetramethrin
CYPHENOTHRIN+TETRAMETHRIN
Cypermethrin+tetramethrin
Cypermethrin+Piperonyl butoxide+tetramethrin
Bioallethrin+Piperonyl butoxide+tetramethrin

Molecular weight:331.4; Physical form:Colourless crystals, with slight pyrethrum-like odour; ( tech. is a colourless to light yellow-brown solid). Density:1.1 (20 °C); Composition:Tech. is c. 92% pure. Melting point:68-70 °C; ( tech., 60-80 °C); Flash point:200 °C (Cleveland open cup); Vapour pressure:2.1 mPa (25 °C); Partition coefficient(n-octanol and water):logP = 4.6 (25 °C); Solubility:In water 1.83 mg/l (25 °C). In acetone, ethanol, methanol, hexane, n-octanol all >2 g/100 ml.; Stability:Sensitive to alkalis and strong acids; DT50 16-20 d ( pH 5), 1 d ( pH 7), <1 h ( pH 9). Stable on storage up to c. 50 °C. Stable in ketones, chloroform, xylene, common aer;

Oral:Acute oral LD₅₀ for rats >5000 mg/kg. Percutaneous:Acute percutaneous LD₅₀ for rabbits >2000 mg/kg. Non-irritant to skin. Inhalation: LC₅₀ (4 h) for rats >2.73 mg/l air.

Ecotoxicology: 
Bees:Toxic to bees.Birds:Acute oral LD₅₀ for bobwhite quail >2250 mg/kg. Dietary LC₅₀ for bobwhite quail and mallard ducks >5620 ppm.Daphnia: EC₅₀ (48 h) 0.11 mg/l.Fish:LC₅₀ (96 h) for rainbow trout 3.7, bluegill sunfish 16 µg/l. 

Environmental fate: 
EHC 98 notes rapid abiotic degradation in air and water, rapid metabolism and excretion in mammals, and no tendency to accumulate in tissues.Animals:In rats, following oral administration, around 95% of tetramethrin (metabolised) is eliminated in the urine and faeces within 5 days. The principal metabolite is 3-hydroxycyclohexan-1,2-dicarboximide (J. Miyamoto et al., J. Agric. BioSoil:Degradation involves cleavage of the ester bond, leading to chrysanthemic acid derivatives and phenoxybenzoic acid. These are further metabolised by hydroxylation and conjugation.

Signal Word:CAUTION; Hazard Class:III(Slightly hazardous)